About the Article
Article Files
[This article belongs to Volume - 70, Issue - 9]
Published on : 2025-09-11 18:53:45
Article Code: AMJ-11-09-2025-12331
Title : Enhanced Colorectal Cancer Therapy via Innovative Nanoparticle Mediated Delivery of Tea Polyphenols
Author(s) : Elena Martinez
Abstract :
Tea polyphenols have demonstrated potential in the prevention and treatment of colorectal cancer. However, its use
in clinical settings has been hampered by drawbacks in terms of stability and bioavailability. This review aims to
explore and evaluate the potential of nanoparticles as efficient delivery vehicles for tea polyphenols in the context
of colorectal cancer therapy. In this review, we summarise studies on the efficacy of tea polyphenols on colorectal
cancer and their limitations for colorectal cancer therapy. Moreover, we also discuss the mechanistic signalling
pathway of tea polyphenols and how nanotechnology improves the limitations. Additionally, the mechanisms
performed using nanoparticles in drug delivery and the significance of nanoparticles for targeted drug delivery were
covered in this review. The future of colorectal cancer therapy may be significantly influenced by the integration of
nanotechnology to deliver tea polyphenols. Nanoparticle-based delivery systems promise to overcome inherent
challenges associated with the bioavailability and targeted delivery of tea polyphenols. By enhancing solubility,
stability, and controlled release, nanotechnology can optimise the therapeutic efficacy of these bioactive compounds.